Puneet Sharma, Ph.D, Fellow AIMBE

Vice President, AI for Healthcare
Siemens Healthineers
Princeton, NJ 08540
Email: sharma.puneet AT siemens-healthineers.com

View Puneet Sharma's profile on LinkedIn

Focus: AI algorithm development and validation, R&D Program Management, Clinical Collaborations.
Technical areas: Artificial Intelligence, Cardiovascular Imaging, Computational Modeling, Numerical Optimization, Inverse Problems, Systems & Controls 		Puneet Sharma
Recent News

  • I'll give a talk at the Society of Cardiovascular Computed Tomography, Innovation Series on AI/ML in Coronary Artery Disease, June 2021
  • I'll participate in the AI MED Clinician Series- Imaging. Roundtable - Real time applications of AI in cardiology, June 2021
  • I'll be presenting a symposium talk titled "Driving AI Innovation in Cardiothoracic CT Imaging" at the upcoming Society for Cardiovascular Computed Tomography (SCCT 2020) Annual Meeting, July 18, 2020.
  • My upcoming talk at the Artificial Intelligence and Machine Learning in Cardiovascular CT Meeting orgainzed by Society for Cardiovascular Computed Tomography (SCCT) April 24, 2020.
  • I'll give an invited talk at the Intel SOLVE event during the Radiological Society of North America (RSNA 2019) Annual meeting, titled "Artificial Intelligence - Implications for Advanced Imaging & Precision Medicine", Dec 4, 2019.
  • My upcoming keynote talk and panel discussion at Medical University of South Carolina (MUSC), during the Innovation Week (May 3, 2019), titled "Artificial Intelligence: Implications for Advanced Imaging and Precision Medicine".
  • Invited talk at the American Society of Nuclear Cardiology (ASNC 2018) Annual meeting, Special session: Machine Learning, Medicine, and Imaging: The Future is Now

Click here for archived news

Recent Journal and Conference Publications
  1. Puneet Sharma,Michael Suehling, Thomas Flohr, Dorin Comaniciu, Artificial Intelligence in Diagnostic Imaging: Status Quo, Challenges, and Future Opportunities, Journal of Thoracic Imaging, May 2020 [url]
  2. Andreas M Fischer, Marwen Eid, Carlo N De Cecco, Mehmet A Gulsun, Marly van Assen, John W Nance, Pooyan Sahbaee, Domenico De Santis, Maximilian J Bauer, Brian E Jacobs, Akos Varga-Szemes, Ismail M Kabakus, Puneet Sharma, Logan J Jackson, U Joseph Schoepf, Accuracy of an Artificial Intelligence Deep Learning Algorithm Implementing a Recurrent Neural Network With Long Short-term Memory for the Automated Detection of Calcified Plaques From Coronary Computed Tomography Angiography , Journal of Thoracic Imaging, May 2020 [url]
  3. Takashi Suzuki, Hiroyuki Takao, Saikiran Rapaka, Soichiro Fujimura, Cosmin Ioan Nita, Yuya Uchiyama, Hiroshi Ohno, Katharina Otani, Chihebeddine Dahmani, Viorel Mihalef, Puneet Sharma, Ashraf Mohamed, Thomas Redel, Toshihiro Ishibashi, Makoto Yamamoto, Yuichi Murayama, Rupture Risk of Small Unruptured Intracranial Aneurysms in Japanese Adults , Stroke . 2020 Feb;51(2):641-643 [url]
  4. Costin Ciusdel, Alexandru Turceaa, Andrei Puiu, LucianItu, Lucian Calmac, Emma Weiss, Cornelia Margineanu, Elisabeta Badila, Martin Berger, Thomas Redel, Tiziano Passerini, Mehmet Gulsun, Puneet Sharma, Deep neural networks for ECG-free cardiac phase and end-diastolic frame detection on coronary angiographies , Computerized Medical Imaging and Graphics Volume 84, September 2020, 10174 [url]
  5. Simon S Martin, Marly van Assen, Saikiran Rapaka, H Todd Hudson Jr, Andreas M Fischer, Akos Varga-Szemes, Pooyan Sahbaee, Chris Schwemmer, Mehmet A Gulsun, Serkan Cimen, Puneet Sharma, Thomas J Vogl, U Joseph Schoepf, Evaluation of a Deep Learning-Based Automated CT Coronary Artery Calcium Scoring Algorithm , JACC Cardiovascular Imaging . 2020 Feb;13(2 Pt 1):524-526. [url]
  6. Adam Spandorfer, Cody Branch, Puneet Sharma, Pooyan Sahbaee, U. Joseph Schoepf, James G. Ravenel, John W. Nance, Deep learning to convert unstructured CT pulmonary angiography reports into structured reports , European Radiology Experimental 2019 Dec; 3: 37 [url]
  7. Saeid Asgari Taghanaki, Yefeng Zheng, S. Kevin Zhou, Bogdan Georgescu, Puneet Sharma, Daguang Xu, Dorin Comaniciu, Ghassan Hamarneh, Combo Loss: Handling Input and Output Imbalance in Multi-Organ Segmentation , Computerized Medical Imaging and Graphics, 2019[url]
  8. Adriaan Coenen, Young-Hak Kim, Mariusz Kruk, Christian Tesche, Jakob De Geer, Akira Kurata, Marisa L. Lubbers, Joost Daemen, Lucian Itu, Saikiran Rapaka, Puneet Sharma, Chris Schwemmer, Anders Persson, U. Joseph Schoepf, Cezary Kepka, Dong Hyun Yang and Koen Nieman, Diagnostic Accuracy of a Machine-Learning Approach to Coronary Computed Tomographic Angiography–Based Fractional Flow Reserve , Circulation: Cardiovascular Imaging. 2018;11:e007217 [url]
  9. Christian Tesche, Carlo N De Cecco, Stefan Baumann, Matthias Renker, Tindal W McLaurin, Taylor M Duguay, Richard R Bayer 2nd, Daniel H Steinberg, Katharine L Grant, Christian Canstein, Chris Schwemmer, Max Schoebinger, Lucian M Itu, Saikiran Rapaka, Puneet Sharma, U Joseph Schoepf, Coronary CT angiography–derived fractional flow reserve: machine learning algorithm versus computational fluid dynamics modeling , Radiology, Vol. 288, No. 1, 2018 [url]
  10. L. Itu, D. Neumann, V. Mihalef, F. Meister, M. Kramer, M. Gulsun, M. Kelm, T. Kühne, Cardioproof, P. Sharma, Non-invasive assessment of patient-specific aortic haemodynamics from four-dimensional flow MRI data , Journal of the Royal Society, Interface Focus, Volume 8, issue 1, 2018 [url]
  11. L. Itu, S. Rapaka, T. Passerini, B. Georgescu, C. Schwemmer, M. Schoebinger, T. Flohr, P. Sharma, D. Comaniciu, A Machine Learning Approach for Computation of Fractional Flow Reserve from Coronary Computed Tomography, Journal of Applied Physiology, Article in Press, 2016[url]



     Click here for full list of publications

Granted US Patents
  1. Artificial intelligence for basal and apical slice identification in cardiac MRI short axis acquisitions, US Patent # 11,232,859, Issue date: January 25, 2022
  2. Personalized assessment of patients with acute coronary syndrome, US Patent # 11,191,490, Issue date: December 7, 2021
  3. Image generation from a medical text report, US Patent # 11,170,891, Issue date: November 9, 2021
  4. Assessment of collateral coronary arteries, US Patent # 11,145,057, Issue date: October 12, 2021
  5. Automatic detection and quantification of the aorta from medical images, US Patent # 11,127,138, Issue date: September 21, 2021
  6. Automatically generating synchronized view and level of concordance of diagnostic exams, US Patent # 11,051,780, Issue date: July 6, 2021
  7. Processing image frames of a sequence of cardiac images, US Patent # 11,051,779, Issue date: July 6, 2021
  8. Performance of machine learning models for automatic quantification of coronary artery disease, US Patent # 11,030,490, Issue date: June 8, 2021
  9. System and method for medical image-based cardio-embolic stroke risk prediction, US Patent # 11,024,404, Issue date: June 1, 2021
  10. Synthetic data-driven hemodynamic determination in medical imaging, US Patent # 10,993,687, Issue date: May 4, 2021
  11. Artificial intelligence for physiological quantification in medical imaging, US Patent # 10,984,905, Issue date: April 20, 2021
  12. Artificial intelligence-based material decomposition in medical imaging, US Patent # 10,973,472, Issue date: April 13, 2021
  13. Method and system for personalized blood flow modeling based on wearable sensor networks, US Patent # 10,971,271, Issue date: April 6, 2021
  14. Determining arterial wall property with blood flow model, US Patent # 10,945,613, Issue date: March 16, 2021
  15. Detection of infarcts using trained network, US Patent # 10,937,205, Issue date: March 2, 2021
  16. Medical image pre-processing at the scanner for facilitating joint interpretation by radiologists and artificial intelligence algorithms, US Patent # 10,929,973, Issue date: February 23, 2021
  17. Structured report data from a medical text report, , US Patent # 10,929,420, Issue date: February 23, 2021
  18. Artificial intelligence-based COPD assessment, US Patent # 10,918,309, Issue date: February 16, 2021
  19. Method and system for clinical decision support with local and remote analytics, US Patent # 10,909,676, Issue date: February 2, 2021
  20. Method and system for machine learning based assessment of fractional flow reserve, US Patent # 10,888,234, Issue date: January 12, 2021
  21. Method and system for artificial intelligence based medical image segmentation, US Patent # 10,878,219, Issue date: December 29, 2020
  22. Method and system for enhancing medical image-based blood flow computations using physiological measurements, US Patent # 10,872,698, Issue date: December 22, 2020
  23. Rapid assessment and outcome analysis for medical patients, US Patent # 10,825,167, Issue date: November 3, 2020
  24. Method and system for non-invasive functional assessment of coronary artery stenosis using flow computations in diseased and hypothetical normal anatomical models, US Patent # 10,803,995, Issue date: October 13, 2020
  25. Vascular segmentation using fully convolutional and recurrent neural networks, US Patent # 10,762,637, Issue date: September 1, 2020
  26. Method and system for assessing a haemodynamic parameter, US Patent # 10,758,200, Issue date: September 1, 2020
  27. Enhanced personalized evaluation of coronary artery disease using an integration of multiple medical imaging techniques, US Patent # 10,758,125, Issue date: September 1, 2020
  28. System and method for interactive patient specific simulation of radiofrequency ablation therapy, US Patent # 10,748,438, Issue date: August 18, 2020
  29. Tissue-to-flow image generation in medical imaging, US Patent # 10,726,546, Issue date: July 28, 2020
  30. Classifying views of an angiographic medical imaging system, US Patent # 10,667,776, Issue date: June 2, 2020
  31. Machine learning based real-time radiation dose assessment, US Patent # 10,645,259, Issue date: May 5, 2020
  32. System and method for learning based magnetic resonance fingerprinting, US Patent # 10,627,470, Issue date: April 21, 2020
  33. Framework for personalization of coronary flow computations during rest and hyperemia, US Patent # 10,622,110, Issue date: April 14, 2020
  34. Personalized assessment of bone health, US Patent # 10,622,102, Issue date: April 14, 2020
  35. Method and system for personalized non-invasive hemodynamic assessment of renal artery stenosis from medical images, US Patent # 10,595,790, Issue date: March 24, 2020
  36. CFD simulation assisted 4D DSA reconstruction, US Patent # 10,580,172, Issue date: March 3, 2020
  37. Machine-learnt prediction of uncertainty or sensitivity for hemodynamic quantification in medical imaging, US Patent # 10,522,253, Issue date: December 31, 2019
  38. Identification of defects in imaging scans, US Patent # 10,521,911, Issue date: December 31, 2019
  39. Learning based methods for personalized assessment, long-term prediction and management of atherosclerosis, US Patent # 10,483,006, Issue date: November 19, 2019
  40. Plaque vulnerability assessment in medical imaging, US Patent # 10,478,130, Issue date: November 19, 2019
  41. Smart editing of image-processing results, US Patent # 10,474,917, Issue date: November 12, 2019
  42. Method and system for purely geometric machine learning based fractional flow reserve, US Patent # 10,463,336, Issue date: November 5, 2019
  43. Method and system for improved hemodynamic computation in coronary arteries, US Patent # 10,460,204, Issue date: October 29, 2019
  44. Non-invasive functional assessment of coronary artery stenosis including simulation of hyperemia by changing resting microvascular resistance, US Patent # 10,373,700, Issue date: August 6, 2019
  45. Non-invasive functional assessment of coronary artery stenosis including simulation of hyperemia by changing resting microvascular resistance, US Patent # 10,354,744, Issue date: July 16, 2019
  46. Patient-specific radiation dose assessment in medical therapy, US Patent # 10,350,434, Issue date: July 16, 2019
  47. Three-dimensional quantitative heart hemodynamics in medical imaging, US Patent # 10,299,862, Issue date: May 28, 2019
  48. Viscoelastic modeling of blood vessels, US Patent # 10,297,341, Issue date: May 21, 2019
  49. Method and system for machine learning based assessment of fractional flow reserve, US Patent # 10,258,244, Issue date: April 16, 2019
  50. Method and system for extracting centerline representation of vascular structures in medical images via optimal paths in computational flow fields, US Patent # 10,206,646, Issue date: February 19, 2019
  51. Fractional flow reserve decision support system, US Patent # 10,192,640, Issue date: January 29, 2019
  52. Coronary computed tomography clinical decision support system, US Patent # 10,176,896, Issue date: January 8, 2019
  53. Method and system for multi-scale anatomical and functional modeling of coronary circulation, US Patent # 10,162,932, Issue date: December 25, 2018
  54. Method and system for hemodynamic computation in coronary arteries, US Patent # 10,134,129, Issue date: November 20, 2018
  55. Method and system for prediction of post-stenting hemodynamic metrics for treatment planning of arterial stenosis, US Patent # 10,130,266 , Issue date: November 20, 2018
  56. Synthetic data-driven hemodynamic determination in medical imaging, US Patent # 10,111,636 , Issue date: October 30, 2018
  57. System and method for determining optimal operating parameters for medical imaging, US Patent #10,074,037, Issue date: September 11, 2018
  58. Determining functional severity of stenosis, US Patent # 10,052,031, Issue date: August 21, 2018
  59. Direct computation of image-derived biomarkers, US Patent # 10,002,419, Issue date:June 19, 2018
  60. Method and system for non-invasive assessment of coronary artery disease, US Patent # 9,999,361, Issue date: June 19, 2018
  61. Method and system for machine learning based assessment of fractional flow reserve, US Patent # 9,974,454, Issue date: May 22, 2018
  62. Synthetic data-driven hemodynamic determination in medical imaging, US Patent # 9,918,690, Issue date: March 20, 2018
  63. Method and system for automated therapy planning for arterial stenosis, US Patent # 9,888,968, Issue date: February 13, 2018
  64. Method and system for vascular disease detection using recurrent neural networks, US Patent # 9,881,372, Issue date: January 30, 2018
  65. System and method for patient specific modeling of liver tumor ablation, US Patent # 9,846,765, Issue date: December 19, 2017
  66. Method and system for vascular disease detection using recurrent neural networks, US Patent # 9,767,557, Issue date: September 19, 2017
  67. Method and system for improved hemodynamic computation in coronary arteries, US Patent # 9,747,525, Issue date: August 29, 2017
  68. Method and system for machine learning based assessment of fractional flow reserve, US Patent # 9,700,219, Issue date: July 11, 2017
  69. Method and system for functional assessment of renal artery stenosis from medical images, US Patent # 9,629,563, Issue date: April 25, 2017
  70. Method and system for non-invasive computation of hemodynamic indices for coronary artery stenosis, US Patent # 9,595,089, Issue date: March 14, 2017
  71. Estimation of a mechanical property of anatomy from medical scan data, US Patent # 9,585,632, Issue date: March 7, 2017
  72. Method and system for machine learning based assessment of fractional flow reserve, US Patent # 9,538,925, Issue date: January 10, 2017
  73. Method and system for blood flow velocity reconstruction from medical images, US Patent # 9,462,954, Issue date: October 11, 2016
  74. Synthetic data-driven hemodynamic determination in medical imaging, US Patent # 9,349,178, Issue date: May 24, 2016
  75. Patient specific planning and simulation of ablative procedures, US Patent # 9,259,287, Issue date: February 16, 2016
  76. Computation of hemodynamic quantities from angiographic data, US Patent # 9,247,918, Issue: February 2, 2016
  77. Method and system for patient-specific computational modeling and simulation for coupled hemodynamic analysis of cerebral vessels, US Patent # 9,141,763, Issue date: September 22, 2015
  78. Method and system for hemodynamic assessment of aortic coarctation from medical image data, US Patent # 9,135,699, Issue date: September 15, 2015
  79. Method and system for advanced measurements computation and therapy planning from medical data and images using a multi-physics fluid-solid heart model, US Patent # 9,129,053, Issue date: September 8, 2015
  80. Method and system for non-invasive assessment of coronary artery disease, US Patent # 9,119,540, Issue date: September 1, 2015
  81. Method and system for patient-specific hemodynamic assessment of virtual stent implantation, US Patent # 8,983,809, Issue date: March 17, 2015
  82. Blood flow computation in vessels with implanted devices, US Patent # 8,965,084, Issue date: February 24, 2015
  83. Method and system for comprehensive patient-specific modeling of the heart, US Patent # 8,682,626, Issue date: March 25, 2014
  84. Method and system for multi-component heart and aorta modeling for decision support in cardiac disease, US Patent # 8,527,251, Issue date: September 3, 2013
  85. Method and system for computational modeling of the aorta and heart, US Patent # 8,224,640, Issue date: July 17, 2012